Command Center

Predictive safety · Enrollment forecast · Anomaly detection · Protocol optimization · ATLAS-204

Live · updates every 5 min

Executive command center

Your trial, predicted.

Real-time view of safety signals 48-72h ahead, enrollment trajectory vs plan, and anomalies across 47 sites. Every decision backed by a model.

High-risk SAEs

3+1

next 72 hours

Enrollment

284+12

of 480 target · 59%

Forecast LPI

Oct 14

18d ahead of plan

Anomalies

14-3

open · 2 critical

Predictive SAE Warnings

4 active · 48–72h window

87%

PROB

0117-0042Cardiac arrhythmiaSEVERE

Predicted onset · next 14h

QTc prolongation +24ms · Concomitant ondansetron · Day-7 troponin elevated

72%

PROB

0203-0011Hepatic dysfunctionMODERATE

Predicted onset · 36-48h

ALT 3.2× ULN trending up · Bilirubin 1.4× · Day-21 dose escalation

64%

PROB

0341-0007Severe hypotensionMODERATE

Predicted onset · 24-72h

BP trending down 4 visits · Hydration concerns flagged

51%

PROB

0117-0089NeutropeniaMILD

Predicted onset · 48-72h

ANC 1,200 trending down · Cycle 3 nadir window

Enrollment Forecast

ML v2.3 · 92% conf

Best case

Sep 28

-32d vs plan

Likely

Oct 14

-18d vs plan

Worst case

Dec 3

+31d vs plan

Actual

Target

95% CI

Anomalies

4 open · z-score filter

Site 0341 · Visit window compliance

z = -2.4

62%

Site 0489 · Query response time

z = +3.1

9.2 days

Site 0117 · ICF re-consent rate

z = -2.1

78%

Site 0203 · Source verification lag

z = +1.9

11 days

Protocol Optimization

AI-generated

Inclusion criteria

Relax eGFR ≥ 60 → ≥ 50

+18% eligible cohort, no safety signal increase

91%

Visit schedule

Combine V5 + V6 if AE-free

Reduce subject burden, save ~$340 per arm visit

87%

Lab schedule

Skip Day-14 chemistry if Day-7 normal

Save ~$220K total, no efficacy loss in modeling

82%