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Portfolio Compliance Index · Live
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AI Coach
Reviewing today's signals.
scanning · audit, deviations, docs, irt
Recent Protocol Deviations
AI-flagged signals on top · last 30 days
View all →
Expiring Documents
Within 30 days · regulatory risk
Manage →
Site Compliance Snapshot
Composite of essential docs + deviation rate + IP accountability
Site matrix →

Command Center

Predictive safety · Enrollment forecast · Anomaly detection · Protocol optimization · ATLAS-204
Live · updates every 5 min
Executive command center
Your trial, predicted.
Real-time view of safety signals 48-72h ahead, enrollment trajectory vs plan, and anomalies across 47 sites. Every decision backed by a model.
High-risk SAEs
3+1
next 72 hours
Enrollment
284+12
of 480 target · 59%
Forecast LPI
Oct 14
18d ahead of plan
Anomalies
14-3
open · 2 critical
Predictive SAE Warnings
8 active · 48–72h window
Enrollment Forecast
ML v2.3 · 92% conf
Best case
Sep 28
-32d vs plan
Likely
Oct 14
-18d vs plan
Worst case
Dec 3
+31d vs plan
Actual
Target
95% CI
Anomalies
14 open · z-score filter
Protocol Optimization
AI-generated

Audit Trail

21 CFR Part 11 · immutable · WHO / WHAT / WHEN / WHY / WHERE
Activity Log
Latest 40 entries · sorted by timestamp desc

Essential Documents

CVs · licenses · GCP · Form 1572 · IRB · consent · investigator brochure
Document Library
Progress bar = time remaining until expiration

Protocol Deviations

Typed · severity-graded · AI-detection enabled
Minor
Major
Critical
AI-detected
Deviation Queue
Open first · critical pinned to top

IRT · Drug Supply

Kits · lots · temperature · shipments · accountability
Inventory
Click any kit for full chain-of-custody history
Available
Dispensed
Quarantine
Expired
In transit
Temperature Monitoring
Site 0117 · refrigerator #3 · 2–8 °C · 72h window

AI Visit Workspace

ATLAS-204 · Site 0117 — Northwell Health · Interim Monitoring · Apr 22, 2026
Pre-visit Ready
Pre-visit analysis complete
18 subjects reviewed. 6 need your attention.
WRLDOS pre-ran source-to-EDC verification on every subject, triangulated risk from deviations, queries, and SAE timing, and drafted your visit findings. You focus on the 6 that matter.
Traditional visit
14h 20m
manual SDV + report
WRLDOS visit
3h 10m
review + decision only
Saved
11h 10m
≈ $1,562 cost avoided
Source OCR
147 docs · 3 engines
SDV comparison
18/18 subjects · 94.2% match
Risk triangulation
7 categories scored
4
CRA review
6 items flagged
5
Generate report
auto-drafted
Subjects AI Pre-verified
Filter by verification status
0 of 6 AI findings accepted · 6 queries auto-drafted

Predictive Site Selection

Score candidate sites before commitment · Replace 90-day feasibility with an afternoon
Feasibility analysis complete
47 sites scored. 12 highly recommended.
WRLDOS ran 6-dimension predictive scoring across candidate sites using 4 years of historical performance data. Recommended portfolio hits enrollment target 38% faster than industry median.
Sites scored
47
across 11 countries
Recommended
score ≥ 85
Enrollment forecast
247d
full enrollment · 95% CI
Time avoided
87d
vs traditional feasibility
Study
ATLAS-204
Therapeutic area
Oncology · NSCLC
Target enrollment
480 subjects
Phase
Phase III
Sort by
0 sites selected for comparison

Patient Screening

AI-matched candidates · Pre-screened eligibility · Screen failure prediction
Candidate funnel · ATLAS-204
47 candidates predicted to pass screening
WRLDOS pre-screened 1,247 EHR records against your I/E criteria, checked concomitant medications against the protocol's prohibited drug list, and predicted screen failure probability for each candidate. Your CRCs engage only the high-probability cohort.
Pool
1,247
EHR records reviewed
Pre-screened
284
22.8% → diagnosis match
Matched
89
31.3% → I/E eligible
Predicted pass
47
52.8% → screen pass likely
Enroll target
38
vs 18 historical avg
Sort by
Candidates
89 patients

Monitoring Visit Report

ATLAS-204 · Site 0117 — Northwell Health · Visit #7
Draft
Protocol
ATLAS-204
Site
0117 · Northwell
PI
Dr. L. Reyes, MD
Visit Type
Interim Monitoring
Visit Date
Apr 18, 2026
CRA
K. Okoye

Source Data Verification

AI: Hit 100% SDV for subjects with open queries — 3 pending
AI: Auto-draft of 6 queries ready — review & dispatch

Findings & Action Items

Auto-saved · 14s ago · v2.4

Settings

Data source · workspace · about
Data Source
Toggle between mock data and your live FastAPI backend
Use live backend
When OFF, the UI uses deterministic mock fixtures shaped to your Phase 1 Pydantic schemas. When ON, every view calls your FastAPI at the base URL below.
API base URL
Default: http://localhost:8000/api
Bearer token (optional)
From POST /api/auth/token. Stored in-memory only.
Connection test
Pings /health on your base URL.
Workspace
Optional momentum layer — off by default, respectful of focus
Show "Today" panel
Sidebar widget showing items closed today and your current compliance streak. Visible nudge toward steady progress.
Show earned badges
Quietly track milestones — Inspection Ready, Zero-Miss Month, Cold-Chain Guardian. Each shows a progress ring; earned ones turn green.
Mapped Endpoints
Every view in WRLDOS maps to these Phase 1 routes from your FastAPI
Design Decisions, Backed by Science
Why WRLDOS looks and feels the way it does
Background #EEF3F9 sharpens sustained attention (Chellappa et al., PLOS ONE 2011). Blue accents #1A5490 activate the locus coeruleus alertness pathway (Alkozei et al., SLEEP 2016). Light mode produces measurably higher cognitive scores across all demographic groups (Ergonomics / Taylor & Francis 2025). Trebuchet MS + Calibri humanist family at ~17:1 contrast meets WCAG AAA / IEC 62366 medical-device minimum. Amber #E8A020 is reserved as the single signal color — used sparingly, so it always means "act now".
Closed
Critical deviation resolved.